Nuclear HMGB1 protects from nonalcoholic fatty liver disease through negative regulation of liver X receptor
Author(s) -
Jean Personnaz,
Enzo Piccolo,
Alizée Dortignac,
Jason S. Iacovoni,
Jérôme Mariette,
Vincent Rocher,
Arnaud Polizzi,
Aurélie Batut,
Simon Deleruyelle,
Lucas Bourdens,
Océane Delos,
Lucie CombesSoia,
Romain Paccoud,
Elsa Moreau,
Frédéric Martins,
Thomas Clouaire,
Fadila Benhamed,
Alexandra Montagner,
Walter Wahli,
Robert F. Schwabe,
Armelle Yart,
Isabelle CastanLaurell,
Justine BertrandMichel,
Odile BurletSchiltz,
Catherine Postic,
PierreDamien Denechaud,
Cédric Moro,
Gaëlle Legube,
ChihHao Lee,
Hervé Guillou,
Philippe Valet,
Cédric Dray,
JeanPhilippe Pradère
Publication year - 2022
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.abg9055
Subject(s) - lipogenesis , steatosis , fatty liver , liver x receptor , nonalcoholic fatty liver disease , hmgb1 , biology , lipotoxicity , nuclear receptor , transcription factor , lipid metabolism , cancer research , endocrinology , medicine , receptor , gene , genetics , disease , insulin resistance , insulin
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