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Mycobacterium tuberculosis clinical isolates carry mutational signatures of host immune environments
Author(s) -
Qingyun Liu,
Jianhao Wei,
Yawei Li,
Mei Wang,
Jun Su,
Yonghui Lu,
Mariana G. López,
Xueqin Qian,
Zhaoqin Zhu,
Haiying Wang,
Mingyun Gan,
Qi Jiang,
YunXin Fu,
Howard Takiff,
Iñaki Comas,
Feng Li,
Xuemei Lu,
Sarah M. Fortune,
Qian Gao
Publication year - 2020
Publication title -
science advances
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aba4901
Subject(s) - mycobacterium tuberculosis , immune system , host (biology) , tuberculosis , biology , microbiology and biotechnology , virology , genetics , medicine , pathology
Massive single-colony sequencing revealed that mutation rates varied between different bacilli from the same patient.

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