Open AccessStructural basis of broad HIV neutralization by a vaccine-induced cow antibody
Author(s) -
Robyn L. Stanfield,
Zachary T. Berndsen,
Ruiqi Huang,
Devin Sok,
Gabrielle Warner Jenkins,
Jonathan L. Torres,
Dennis R. Burton,
Andrew B. Ward,
Ian A. Wilson,
Vaughn V. Smider
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aba0468
Subject(s) - neutralization , virology , mutagenesis , antibody , human immunodeficiency virus (hiv) , hiv vaccine , biology , immunology , virus , computational biology , mutation , genetics , vaccine trial , gene
Structure and mutagenesis studies show that a potent vaccine-elicited cow bnAb binds with a compact footprint to HIV gp120 CD4bs.
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