Open AccessMre11 exonuclease activity removes the chain-terminating nucleoside analog gemcitabine from the nascent strand during DNA replication
Author(s) -
L. Boeckemeier,
Rolf Kraehenbuehl,
Andrea Keszthelyi,
Marie-Fabrice Uwamahoro Gasasira,
Ellen G Ver,
Richard Beardmore,
Cathrine Broberg Vågbø,
Daniel Chaplin,
Simon Gollins,
Hans E. Krokan,
Sarah Lambert,
Bèla Paizs,
Edgar Hartsuiker
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaz4126
Subject(s) - exonuclease , dna replication , dna , nucleoside , replication (statistics) , nucleoside analogue , chemistry , microbiology and biotechnology , computational biology , biology , genetics , dna polymerase , virology
Mre11 exonuclease activity removes gemcitabine from the nascent strand during DNA replication.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom