A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates
Author(s) -
Virginia M. Stone,
Minna M. Hankaniemi,
Olli H. Laitinen,
AmirBabak SioofyKhojine,
Ang Lin,
Isabel María Díaz Lozano,
Magdalena Mazur,
Varpu Marjomäki,
Karin Loré,
Heikki Hyöty,
Vesa P. Hytönen,
Malin FlodströmTullberg
Publication year - 2020
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaz2433
Subject(s) - coxsackievirus , immunogenicity , myocarditis , virology , adjuvant , medicine , immunology , antibody , immunity , virus , immune system , enterovirus , cardiology
A proof-of-concept study shows the generation of an immunogenic hexavalent Coxsackie B virus vaccine that prevents disease.
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