Open AccessSpCas9 activity prediction by DeepSpCas9, a deep learning–based model with high generalization performance
Author(s) -
Hui Kwon Kim,
Younggwang Kim,
Sungtae Lee,
Seonwoo Min,
Jung Yoon Bae,
Jae Woo Choi,
Jinman Park,
Dongmin Jung,
Sungroh Yoon,
Seokjoong Kim
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aax9249
Subject(s) - generalization , computer science , artificial intelligence , deep learning , indel , machine learning , biology , mathematics , gene , genetics , mathematical analysis , genotype , single nucleotide polymorphism
A deep learning–based model predicts activity of a widely used genome editing tool in a highly accurate manner.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom