Open AccessAllosteric modulation of nucleoporin assemblies by intrinsically disordered regions
Author(s) -
Bartlomiej J. Blus,
Junseock Koh,
Aleksandra Krolak,
HyukSoo Seo,
Elias Coutavas,
Günter Blobel
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aax1836
Subject(s) - nucleoporin , allosteric regulation , intrinsically disordered proteins , biophysics , nuclear pore , chemistry , microbiology and biotechnology , biology , nuclear transport , biochemistry , enzyme , cell nucleus , cytoplasm
Kap121 interacts with an intrinsically disordered region of Nup53 to allosterically modulate Nup53 binding to partner nucleoporins.
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