Open AccessAntiviral activity of a purine synthesis enzyme reveals a key role of deamidation in regulating protein nuclear import
Author(s) -
Junhua Li,
Jun Zhao,
Simin Xu,
Shu Zhang,
Junjie Zhang,
Jun Xiao,
Ruoyun Gao,
Mao Tian,
Yi Arial Zeng,
Katie Lee,
Vera L. Tarakanova,
Ke Lan,
Hao Feng,
Pinghui Feng
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aaw7373
Subject(s) - deamidation , lytic cycle , purine , enzyme , nucleotide , biochemistry , purine metabolism , chemistry , biology , virology , virus , gene
A nucleotide metabolic enzyme restricts viral lytic replication via protein deamidation.
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