The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium | Zendy

John S. Satterlee | Zendy; Lisa H. Chadwick | Zendy; Frederick L. Tyson | Zendy; Kim McAllister | Zendy; Jill M. Beaver | Zendy; Linda S. Birnbaum | Zendy; Nora D. Volkow | Zendy; Elizabeth L. Wilder | Zendy; James M. Anderson | Zendy; Ananda L. Roy | Zendy

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The NIH Common Fund/Roadmap Epigenomics Program: Successes of a comprehensive consortium

Author(s) -

John S. Satterlee,

Lisa H. Chadwick,

Frederick L. Tyson,

Kim McAllister,

Jill M. Beaver,

Linda S. Birnbaum,

Nora D. Volkow,

Elizabeth L. Wilder,

James M. Anderson,

Ananda L. Roy

Publication year - 2019

Publication title -

science advances

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.928

H-Index - 146

ISSN - 2375-2548

DOI - 10.1126/sciadv.aaw6507

Subject(s) - epigenomics , computer science , computational biology , bioinformatics , data science , medicine , biology , genetics , dna methylation , gene expression , gene

We outline the reasons why the Roadmap Epigenomics Program, as a group science effort, is a success story. The NIH Roadmap Epigenomics Program was launched to deliver reference epigenomic data from human tissues and cells, develop tools and methods for analyzing the epigenome, discover novel epigenetic marks, develop methods to manipulate the epigenome, and determine epigenetic contributions to diverse human diseases. Here, we comment on the outcomes from this program: the scientific contributions made possible by a consortium approach and the challenges, benefits, and lessons learned from this group science effort.

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