Open AccessMAGE cancer-testis antigens protect the mammalian germline under environmental stress
Author(s) -
Klementina Fon Tacer,
Marhiah C. Montoya,
Melissa J. Oatley,
Tessa Lord,
Jon M. Oatley,
Jonathon Klein,
Ramya Ravichandran,
Heather Tillman,
Minsoo Kim,
Jon P. Connelly,
Shondra M. PruettMiller,
Angie L. Bookout,
Emily Binshtock,
Marcin M. Kamiński,
Patrick Ryan Potts
Publication year - 2019
Publication title -
science advances
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.928
H-Index - 146
ISSN - 2375-2548
DOI - 10.1126/sciadv.aav4832
Subject(s) - germline , biology , environmental stress , gene , cancer , genetics , antigen , evolutionary biology
Mammals evolved testis-specificMage-a genes to protect the male germline under starvation stress and are co-opted in cancer.
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