Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence
Author(s) -
Boying Guo,
Alicia RodriguezGabin,
A.E. Prota,
Tobias Mühlethaler,
Nan Zhang,
Kenny Ye,
Michel O. Steinmetz,
Susan Band Horwitz,
Amos B. Smith,
Hayley M. McDaid
Publication year - 2020
Publication title -
molecular pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.469
H-Index - 198
eISSN - 1521-0111
pISSN - 0026-895X
DOI - 10.1124/mol.119.117457
Subject(s) - taxane , tubulin , senescence , paclitaxel , stereochemistry , chemistry , microtubule , cytotoxicity , chemotherapy , ligand (biochemistry) , cancer research , cancer , biology , pharmacology , biochemistry , in vitro , breast cancer , receptor , microbiology and biotechnology , genetics
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