Excitation of polymer-shelled contrast agents with high-frequency ultrasound | Zendy

Jeffrey A. Ketterling | Zendy; Jonathan Mamou | Zendy; John S. Allen | Zendy; Orlando Aristizábal | Zendy; Rene G. Williamson | Zendy; Daniel H. Turnbull | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Excitation of polymer-shelled contrast agents with high-frequency ultrasound

Author(s) -

Jeffrey A. Ketterling,

Jonathan Mamou,

John S. Allen,

Orlando Aristizábal,

Rene G. Williamson,

Daniel H. Turnbull

Publication year - 2006

Publication title -

the journal of the acoustical society of america

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.619

H-Index - 187

eISSN - 1520-8524

pISSN - 0001-4966

DOI - 10.1121/1.2401270

Subject(s) - contrast (vision) , excitation , high frequency ultrasound , ultrasound , acoustics , materials science , high contrast , optics , physics , quantum mechanics

Few experimental and complementary theoretical studies have investigated high-frequency (>20 MHz) nonlinear responses from polymer-shelled ultrasound contrast agents. Three polymer agents with different shell properties were examined for their single-bubble backscatter when excited with a 40 MHz tone burst. Higher-order harmonic responses were observed for the three agents; however, their occurrence was at least partly due to nonlinear propagation. Only one of the agents (1.1 microm mean diameter) showed a subharmonic response for longer excitations (approximately 10-15 cycles) and midlevel pressure excitations ( 2.5 MPa). Theoretical calculations of the backscattered spectrum revealed behavior similar to the experimental results in specific parameter regimes.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research