Fabrication and characterization of carbon nanotube field-effect transistor biosensors | Zendy

Matthew R. Leyden | Zendy; Canan Schuman | Zendy; Tal Sharf | Zendy; J. W. Kevek | Zendy; Vincent T. Remcho | Zendy; Ethan D. Minot | Zendy

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Fabrication and characterization of carbon nanotube field-effect transistor biosensors

Author(s) -

Matthew R. Leyden,

Canan Schuman,

Tal Sharf,

J. W. Kevek,

Vincent T. Remcho,

Ethan D. Minot

Publication year - 2010

Publication title -

proceedings of spie, the international society for optical engineering/proceedings of spie

Language(s) - English

Resource type - Conference proceedings

SCImago Journal Rank - 0.192

H-Index - 176

eISSN - 1996-756X

pISSN - 0277-786X

DOI - 10.1117/12.861329

Subject(s) - biosensor , fabrication , nanotechnology , carbon nanotube , field effect transistor , materials science , characterization (materials science) , transistor , carbon nanotube field effect transistor , engineering , electrical engineering , voltage , medicine , alternative medicine , pathology

We report the fabrication of carbon nanotube field-effect transistors for biosensing applications and the development of protocols for reliable protein and DNA sensing. The sensing method we employ is 'label free', relying only on the intrinsic charge of the biological molecule of interest. We discuss fabrication issues that we have solved, for example the preparation of clean surfaces, and the sensing protocol issues that we have encountered. Polylysine and ss-dna, highly charged biological molecules, are used as model systems to illustrate the performance of our biosensors.

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