Open AccessRefractive index tomography of turbid media by bifocal optical coherence refractometry
Author(s) -
Andrei V. Zvyagin,
Sergey Alexandrov,
Dilusha Silva,
Timothy R. Hillman,
Julian J. Armstrong,
Takuya Tsuzuki,
David D. Sampson
Publication year - 2004
Publication title -
proceedings of spie, the international society for optical engineering/proceedings of spie
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 0.192
H-Index - 176
eISSN - 1996-756X
pISSN - 0277-786X
DOI - 10.1117/12.531272
Subject(s) - optical coherence tomography , refractometry , optics , refractive index , optical tomography , tomography , gradient index optics , tomographic reconstruction , lens (geology) , coherence (philosophical gambling strategy) , materials science , physics , quantum mechanics
We demonstrate tomographic imaging of the refractive index of turbid media using bifocal optical coherence refractometry (BOCR). The technique, which is a variant of optical coherence tomography, is based on the measurement of the optical pathlength difference between two foci simultaneously present in a medium of interest. We describe a new method to axially shift the bifocal optical pathlength that avoids the need to physically relocate the objective lens or the sample during an axial scan, and present an experimental realization based on an adaptive liquid-crystal lens. We present experimental results, including video clips, which demonstrate refractive index tomography of a range of turbid liquid phantoms, as well as of human skin in vivo.12 page(s
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