Development of a 3D ultrasound system to investigate post-hemorrhagic hydrocephalus in pre-term neonates | Zendy

Jessica Kishimoto | Zendy; D. Lee | Zendy; Keith St. Lawrence | Zendy; Walter Romano | Zendy; Aaron Fenster | Zendy; Sandrine de Ribaupierre | Zendy

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Development of a 3D ultrasound system to investigate post-hemorrhagic hydrocephalus in pre-term neonates

Author(s) -

Jessica Kishimoto,

D. Lee,

Keith St. Lawrence,

Walter Romano,

Aaron Fenster,

Sandrine de Ribaupierre

Publication year - 2013

Publication title -

proceedings of spie, the international society for optical engineering/proceedings of spie

Language(s) - English

Resource type - Conference proceedings

SCImago Journal Rank - 0.192

H-Index - 176

eISSN - 1996-756X

pISSN - 0277-786X

DOI - 10.1117/12.2006646

Subject(s) - ventriculomegaly , hydrocephalus , ultrasound , lateral ventricles , medicine , intraventricular hemorrhage , cerebral ventricle , ventricular system , shunt (medical) , microbubbles , shunting , volume (thermodynamics) , left ventricles , cardiology , radiology , ventricle , fetus , pathology , gestational age , pregnancy , genetics , physics , quantum mechanics , biology

Clinical intracranial ultrasound (US) is performed as a standard of care on neonates at risk of intraventricular hemorrhaging (IVH) and is also used after a diagnosis to monitor for potential ventricular dilation. However, it is difficult to estimate the volume of ventricles with 2D US due to their irregular shape. We developed a 3D US system to be used as an adjunct to a clinical system to investigate volumetric changes in the ventricles of neonates with IVH. Our system has been found have an error of within 1% of actual distance measurements in all three directions and volume measurements of manually segmented volumes from phantoms were not statistically significantly different from the actual values (p>0.3). Interobserver volume measurements of the lateral ventricles in a patient with grade III IVH found no significant differences between measurements. There is the potential to use this system in IVH patients to monitor the progression of ventriculomegaly over time.

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