Stimuli-responsive command polymer surface for generation of protein gradients | Zendy

Leonid Ionov | Zendy; Nikolay Houbenov | Zendy; Alexander Sidorenko | Zendy; Manfred Stamm | Zendy; Sergiy Minko | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Stimuli-responsive command polymer surface for generation of protein gradients

Author(s) -

Leonid Ionov,

Nikolay Houbenov,

Alexander Sidorenko,

Manfred Stamm,

Sergiy Minko

Publication year - 2009

Publication title -

biointerphases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.633

H-Index - 45

eISSN - 1934-8630

pISSN - 1559-4106

DOI - 10.1116/1.3119722

Subject(s) - polymer , chemistry , biophysics , nanotechnology , surface (topology) , materials science , biology , geometry , mathematics , organic chemistry

Mixed polyelectrolyte brushes with a composition gradient were used as a platform for fabrication of stimuli-responsive command surfaces to control the generation of concentration gradients of adsorbed protein molecules. Switching between homogeneously adsorbed protein layers and adsorbed layers with protein concentration gradients was achieved by changing the pH of protein aqueous solutions. Protein adsorption and the direction of the adsorption gradient were tuned and also turned off and on or reversed by tuning the proton concentration in the pH range 4.0-8.6.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research