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Radiofrequency ablation (RFA) has emerged as an alternative treatment modality for treating various tumors with minimum intervention. The application of RFA in treating breast tumor is still in its infancy stage. Nevertheless, promising results have been obtained while treating early stage localized breast cancer with RFA procedure. The outcome of RFA is tremendously dependent on the precise insertion of the electrode into the geometric center of the tumor. However, there remains plausible chances of inaccuracies in the electrode placement that can result in slight displacement of the electrode tip from the actual desired location during temperature-controlled RFA application. The present numerical study aims at capturing the influence of inaccuracies in electrode placement on the input energy, treatment time and damage to the surrounding healthy tissue during RFA of breast tumor. A thermo-electric analysis has been performed on three-dimensional heterogeneous model of multilayer breast with an embedded early stage spherical tumor of 1.5 cm. The temperature distribution during the RFA has been obtained by solving the coupled electric field equation and Pennes bioheat transfer equation, while the ablation volume has been computed using the Arrhenius cell death model. It has been found that significant variation in the energy consumption, time required for complete tumor necrosis, and the shape of ablation volume among different positions of the electrode considered in this study are prevalent.

Quantification of Thermal Injury to the Healthy Tissue Due to Imperfect Electrode Placements During Radiofrequency Ablation of Breast Tumor