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Seizure Prediction With Spectral Power of EEG Using Cost-Sensitive Support Vector Machines
Author(s) -
Yun Park,
Théoden I. Netoff,
Keshab K. Parhi
Publication year - 2010
Publication title -
journal of medical devices
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.242
H-Index - 29
eISSN - 1932-619X
pISSN - 1932-6181
DOI - 10.1115/1.3455144
Subject(s) - ictal , electroencephalography , false positive paradox , support vector machine , pattern recognition (psychology) , feature vector , artificial intelligence , computer science , sensitivity (control systems) , speech recognition , psychology , neuroscience , engineering , electronic engineering
A patient-specific seizure prediction algorithm is proposed using a classifier to differentiate pre-ictal from inter-ictal EEG signals. The spectral power of EEG processed in four different fashions is used as features: raw, time-differential, space-differential, and time/space-differential EEG. The features are classified using cost-sensitive support vector machines by the double cross-validation methodology. The proposed algorithm has been applied to EEG recordings of 18 patients in the Freiburg EEG database, totaling 80 seizures and 437 h long inter-ictal recordings. Classification with the feature obtained from time/space-differential ECoG demonstrates the performance of 86.25% sensitivity and 0.1281 false positives per hour in out-of-sample testing.

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