Myoinositol: from gametes to embryonic development

Myoinositol (MI) is the main component of inositols family, and is widely distributed in cells and eukaryotic tissues. Physiologically, is involved in cell growth, lipid synthesis, cell cytogenesis, and morphogenesis. Growing evidence shows that MI, through the intracellular Ca2+ release, regulates a variety of signaling pathways including those relating to gametes development, like oocyte maturation, fertilization and embryonic development. It is studied for the treatment of several disorders like polycystic ovary syndrome and metabolic syndrome, as well as the improvement of gametes quality, the clinical outcome of IVF, from gametes to embryonic development, until the end of pregnancy.