LIPOSOME AS TRANSDERMAL CARRIER FOR LABISIA PUMILA AND FICUS DELTOIDEA WATER EXTRACTS | Zendy

Nur Zatul Iradah Roslan | Zendy; Siti Maria Abdul Ghani | Zendy; Nurul Bashirah Yusof | Zendy; Azila Abdul Aziz | Zendy

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LIPOSOME AS TRANSDERMAL CARRIER FOR LABISIA PUMILA AND FICUS DELTOIDEA WATER EXTRACTS

Author(s) -

Nur Zatul Iradah Roslan,

Siti Maria Abdul Ghani,

Nurul Bashirah Yusof,

Azila Abdul Aziz

Publication year - 2017

Publication title -

jurnal teknologi

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.191

H-Index - 22

eISSN - 2180-3722

pISSN - 0127-9696

DOI - 10.11113/jt.v79.10205

Subject(s) - transdermal , chemistry , liposome , zeta potential , chromatography , traditional medicine , permeation , pharmacology , membrane , materials science , medicine , biochemistry , nanotechnology , nanoparticle

In this study, liposome has been investigated as the potential transdermal carrier for Labisia pumila (Lp) and Ficus deltoidea (Fd) . The encapsulation efficiency, zeta potential, particle size and transdermal transport properties of the herbal extracts loaded liposomes were determined to characterize the delivery system. The entrapment efficiency for Lipo- Lp and Lipo- Fd were 35.47 ± 2.71% and 31.23 ± 7.65%, respectively. The average diameter were153.35nm and 131.9nm, respectively and the zeta potential were -47.2 and -46.8, respectively. The permeability and partition coefficient (K) of Lipo- Lp were 1.31cm h -1 and 10.05, respectively and the permeability and partition coefficient (K) of Lipo- Fd were 1.28cm h -1 and 7.62, respectively. Labisia pumila and Ficus deltoidea loaded liposomes showed better transdermal permeation compared to un-encapsulated Labisia pumila and Ficus deltoidea indicative of potential actives herbal cosmetic formulations.

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