Electrical Intramuscular Stimulation in Osteoarthritis Enhances the Inhibitory Systems in Pain Processing at Cortical and Cortical Spinal System | Zendy

Maria da Graca-Tarragó | Zendy; Alícia Deitos | Zendy; Aline Patrícia Brietzke | Zendy; Iraci Lucena da Silva Torres | Zendy; Luciana Paula Cadore Stefani | Zendy; Felipe Fregni | Zendy; Wolnei Caumo | Zendy

Open Access

Electrical Intramuscular Stimulation in Osteoarthritis Enhances the Inhibitory Systems in Pain Processing at Cortical and Cortical Spinal System

Author(s) -

Maria da Graca-Tarragó,

Alícia Deitos,

Aline Patrícia Brietzke,

Iraci Lucena da Silva Torres,

Luciana Paula Cadore Stefani,

Felipe Fregni,

Wolnei Caumo

Publication year - 2015

Publication title -

pain medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.893

H-Index - 97

eISSN - 1526-4637

pISSN - 1526-2375

DOI - 10.1111/pme.12930

Subject(s) - transcranial magnetic stimulation , osteoarthritis , visual analogue scale , evoked potential , primary motor cortex , inhibitory postsynaptic potential , stimulation , anesthesia , medicine , motor cortex , psychology , silent period , neuroscience , pathology , alternative medicine

To determine if in knee osteoarthritis (KOA), one session of active electrical intramuscular stimulation (a-EIMS) compared with sham causes an effect on the motor cortex excitability parameters [motor evoked potential (MEP; the primary outcome), short intracortical inhibition (SICI), intracortical facilitation (ICF) and cortical silent period (CSP)] and pain measurements [pain pressure threshold (PPT); visual analog scale (VAS) and change in numerical pain scale (NPS 0-10 ) during the conditioned pain modulation (CPM)-task]. This study also set out to determine if serum brain-derived neurotrophic factor (BDNF) mediates the effect of treatment on the cortical spinal system as assessed by MEP and PPT.

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