Open AccessDifferential Effects of Oxycodone, Hydrocodone, and Morphine on Activation Levels of Signaling Molecules
Author(s) -
Michael A. Emery,
M.L. Shawn Bates,
Paul J. Wellman,
Shoshana Eitan
Publication year - 2015
Publication title -
pain medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.893
H-Index - 97
eISSN - 1526-4637
pISSN - 1526-2375
DOI - 10.1111/pme.12918
Subject(s) - quinpirole , oxycodone , opioid , pharmacology , agonist , medicine , morphine , opioid receptor , dopamine receptor d3 , μ opioid receptor , dopamine , hydromorphone , dopamine receptor d2 , endocrinology , receptor
Opioids alter the responses of D2-like dopamine receptors (D2DRs), known to be involved in the pathology of addiction and other mental illnesses. Importantly, our recent results demonstrated that various opioids differentially modulate the behavioral responses of D2DRs.
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