Open AccessHow Effective Are Lifestyle Changes in the Prevention of Type 2 Diabetes Mellitus?
Author(s) -
PiSunyer F. Xavier
Publication year - 2007
Publication title -
nutrition reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.958
H-Index - 150
eISSN - 1753-4887
pISSN - 0029-6643
DOI - 10.1111/j.1753-4887.2007.tb00287.x
Subject(s) - medicine , dyslipidemia , impaired glucose tolerance , obesity , insulin resistance , diabetes mellitus , type 2 diabetes mellitus , type 2 diabetes , weight loss , coronary heart disease , endocrinology
Obesity and impaired glucose tolerance are associated with a greater risk for a number of conditions, including insulin resistance, diabetes mellitus, hypertension, dyslipidemia, coagulation abnormalities, inflammatory markers, and coronary heart disease. Lifestyle changes can delay or prevent the development of type 2 diabetes in patients with obesity and impaired glucose tolerance. The risks improve with weight loss and increased physical activity. A decrease of 7% to 10% or more from baseline weight can have a significant effect. This has now been documented in a number of randomized, controlled studies.