Open AccessDietary Nitrates, Nitrites, and N‐Nitroso Compounds and Cancer Risk: A Review of the Epidemiologic Evidence
Author(s) -
Eichholzer Monika,
Gutzwiller Felix
Publication year - 1998
Publication title -
nutrition reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.958
H-Index - 150
eISSN - 1753-4887
pISSN - 0029-6643
DOI - 10.1111/j.1753-4887.1998.tb01721.x
Subject(s) - nitroso compounds , carcinogen , medicine , cancer , stomach cancer , animal studies , environmental health , chemistry , biochemistry , organic chemistry
Experimental animal studies have shown N‐nitroso compounds (NOC) to be potent carcinogens. Epidemiologic evidence of the carcinogenic potential of dietary NOC and precursor nitrates and nitrites in humans remains inconclusive with regard to the risk of stomach, brain, esophageal, and nasopharyngeal cancers. Inadequate available data could obscure a small to moderate effect of NOC.