Open AccessIs Acute High‐Dose Secondhand Smoke Exposure Always Harmful to Microvascular Function in Healthy Adults?
Author(s) -
Bard Robert L.,
Dvonch Joseph T.,
Kaciroti Niko,
Lustig Susan A.,
Brook Robert D.
Publication year - 2010
Publication title -
preventive cardiology
Language(s) - English
Resource type - Journals
eISSN - 1751-7141
pISSN - 1520-037X
DOI - 10.1111/j.1751-7141.2010.00074.x
Subject(s) - medicine , blood pressure , cardiology , secondhand smoke , diastole , hemodynamics , vasodilation , compliance (psychology) , environmental health , psychology , social psychology
Prev Cardiol. Long‐term exposure to secondhand smoke (SHS) is associated with impaired vascular function. The authors investigated the vascular and blood pressure (BP) reactions to acute SHS exposure. Twenty‐five healthy nonsmoking adults underwent a 1‐hour exposure to SHS (mean fine particulate matter <2.5 μm level=315±116 μg/m 3 ). Microvascular endothelial‐dependent vasodilatation (EDV) (EndoPAT, Itamar Medical, Caesarea, Israel) and aortic hemodynamics/compliance (SphygmoCor, AtCor Medical, West Ryde, Australia) were measured before and after the SHS exposure with BP measured every 15 minutes during and for a 24‐hour period before and after the exposure. SHS exposure did not change EDV, aortic hemodynamics, arterial compliance, or 24‐hour BP. However, diastolic BP significantly increased during the SHS exposure period by 3.4±5.6 mm Hg. Our brief SHS exposure did not impair microvascular endothelial function or arterial compliance in healthy nonsmoking adults, but brachial diastolic BP increased. Prev Cardiol. 2010;13:175–179. © 2010 Wiley Periodicals, Inc.