Open AccessResting Heart Rate and Metabolic Syndrome in Patients With Diabetes and Coronary Artery Disease in Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial
Author(s) -
Rana Jamal S.,
Hardison Regina M.,
PopBusui Rodica,
Brooks Maria M.,
Jones Teresa L. Z.,
Nesto Richard W.,
Bourassa Martial G.
Publication year - 2010
Publication title -
preventive cardiology
Language(s) - English
Resource type - Journals
eISSN - 1751-7141
pISSN - 1520-037X
DOI - 10.1111/j.1751-7141.2010.00067.x
Subject(s) - medicine , cardiology , diabetes mellitus , coronary artery disease , revascularization , angioplasty , metabolic syndrome , ejection fraction , type 2 diabetes , population , coronary artery bypass surgery , artery , myocardial infarction , heart failure , obesity , endocrinology , environmental health
The relation between the metabolic syndrome (MetS) and resting heart rate (rHR) in patients with diabetes and coronary artery disease is unknown. The authors examined the cross‐sectional association at baseline between components of the MetS and rHR and between rHR and left ventricular ejection fraction in the population from the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) randomized clinical trial. The mean rHR in the MetS group was significantly higher than in those without (68.4±12.3 vs 65.6±11.8 beats per min, P=.0017). The rHR was higher (P<.001 for trend) with increasing number of components for MetS. Linear regression analyses demonstrated that as compared to individuals without MetS, rHR was significantly higher in participants with MetS (regression coefficient, 2.9; P=.0015). In patients with type 2 diabetes and coronary artery disease, the presence of higher rHR is associated with increasing number of criteria of MetS and the presence of ventricular dysfunction. Prev Cardiol. 2010;13:112–116. © 2009 Wiley Periodicals, Inc.