Open AccessCardiovascular Nursing on Human Genomics: What Do Cardiovascular Nurses Need to Know About Congestive Heart Failure?
Author(s) -
Frazier Lorraine,
Wung ShuFen,
Sparks Elizabeth,
Eastwood Cathy
Publication year - 2009
Publication title -
progress in cardiovascular nursing
Language(s) - English
Resource type - Journals
eISSN - 1751-7117
pISSN - 0889-7204
DOI - 10.1111/j.1751-7117.2009.00039.x
Subject(s) - medicine , heart failure , cardiomyopathy , coronary artery disease , cardiology , pharmacogenetics , etiology , intensive care medicine , disease , genetics , biology , genotype , gene
This paper presents the main causes of heart failure (HF) and an update on the genetics studies on each cause. The review includes a delineation of the etiology and fundamental pathophysiology of HF and provides rational for treatment for the patient and family. Various cardiomyopathies are discussed, including primary cardiomyopathies, mixed cardiomyopathies, cardiomyopathies that involve altered cardiac muscle along with generalized multiorgan disorders, and various cardiovascular conditions, such as coronary artery disease (ischemic cardiomyopathy) and hypertension (hypertensive cardiomyopathy). A brief review of pharmacogenetics and HF is presented. The application of the genetic components of cardiomyopathy and pharmacogenetics is included to enhance cardiovascular nursing care.