Open AccessRoles of F‐box Proteins in Plant Hormone Responses
Author(s) -
YU Haichuan,
WU Jiao,
XU Nanfei,
PENG Ming
Publication year - 2007
Publication title -
acta biochimica et biophysica sinica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.771
H-Index - 57
eISSN - 1745-7270
pISSN - 1672-9145
DOI - 10.1111/j.1745-7270.2007.00358.x
Subject(s) - f box protein , skp1 , ubiquitin ligase , cullin , leucine rich repeat , proteolysis , ubiquitin , biology , ddb1 , biochemistry , microbiology and biotechnology , computational biology , receptor , enzyme , gene
The F‐box protein is an important component of the E3 ubiquitin ligase Skp1‐Cullin‐F‐box protein complex. It binds specific substrates for ubiquitin‐mediated proteolysis. The F‐box proteins contain a signature F‐box motif at their amino‐terminus and some protein‐protein interaction motifs at their carboxy‐terminus, such as Trp‐Asp repeats or leucine rich repeats. Many F‐box proteins have been identified to be involved in plant hormone response as receptors or important medial components. These breakthrough findings shed light on our current understanding of the structure and function of the various F‐box proteins, their related plant hormone signaling pathways, and their roles in regulating plant development.