Open AccessPostnatal Developmental Expression of Calbindin, Calretinin and Parvalbumin in Mouse Main Olfactory Bulb
Author(s) -
QIN ZhaoPing,
YE ShuMing,
DU JiZeng,
SHEN GongYu
Publication year - 2005
Publication title -
acta biochimica et biophysica sinica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.771
H-Index - 57
eISSN - 1745-7270
pISSN - 1672-9145
DOI - 10.1111/j.1745-7270.2005.00031.x
Subject(s) - olfactory bulb , parvalbumin , calretinin , granule cell , calbindin , biology , olfactory system , endocrinology , olfactory nerve , medicine , immunohistochemistry , dentate gyrus , microbiology and biotechnology , neuroscience , central nervous system , immunology
The distribution of calbindin, calretinin and parvalbumin during the development of the mouse main olfactory bulb (MOB) was studied using immunohistochemistry techniques. The results are as follows: (1) calbindin‐immunoreactive profiles were mainly located in the glomerular layer, and few large calbindin‐immunoreactive cells were found in the subependymal layer of postnatal day 10 (P1 0) to postnatal day 40 (P40) mice; (2) no calbindin was detected in the mitral cell layer at any stage; (3) calretinin‐immunoreactive profiles were present in all layers of the main olfactory bulb at all stages, especially in the olfactory nerve layer, glomerular layer and granule cell layer; (4) parvalbumin‐immunoreactive profiles were mainly located in the external plexiform layer (except for P10 mice); (5) weakly stained parvalbumin‐immunoreactive profiles were present in the glomerular layer at all stages; and (6) no parvalbumin was detected in the mitral cell layer at any stage. Edited by: You‐Shang ZHANG