Open AccessLimited Wegener's granulomatosis of the epididymis and testis
Author(s) -
Lee ShangSen,
Tang ShouHung,
Sun GuangHuan,
Yu ChengPing,
Jin JongShiaw,
Chang SunYran
Publication year - 2006
Publication title -
asian journal of andrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 74
eISSN - 1745-7262
pISSN - 1008-682X
DOI - 10.1111/j.1745-7262.2006.00207.x
Subject(s) - orchiectomy , medicine , epididymis , pathology , testicle , giant cell , fibrinoid necrosis , anti neutrophil cytoplasmic antibody , vasculitis , anatomy , surgery , disease , andrology , sperm
A case is presented of Wegener's granulomatosis limited to the testis and epididymis, simultaneously, in a 69‐year‐old man. Orchiectomy was carried out through an inguinal incision under the presumptive diagnosis of a right testicular tumor. A hard, irregular mass occupied the upper testicle and a portion of the epididymal head was visualized. Histopathologic examination of the specimen showed granulomatous inflammation of the testis and epididymis with prominent angiocentric granulomata in the walls of arteries, veins and foci of fibrinoid necrosis, surrounded by palisading inflammatory cells with a few giant cells. The diagnosis of limited Wegener's granulomatosis was considered, although antineutrophil cytoplasmic antibody (c‐ANCA) test was negative 2 weeks after orchiectomy. The patient showed an excellent response after local complete excision. He remains free of disease 18 months after orchiectomy. Edited by Ching‐Shwun Lin