Open AccessDecoding C aulobacter development
Author(s) -
Kirkpatrick Clare L.,
Viollier Patrick H.
Publication year - 2012
Publication title -
fems microbiology reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.91
H-Index - 212
eISSN - 1574-6976
pISSN - 0168-6445
DOI - 10.1111/j.1574-6976.2011.00309.x
Subject(s) - caulobacter crescentus , cytokinesis , biology , microbiology and biotechnology , cell division , genetics , gene , computational biology , cell cycle , cell
C aulobacter crescentus uses a multi‐layered system of oscillating regulators to program different developmental fates into each daughter cell at division. This is achieved by superimposing gene expression, subcellular localization, phosphorylation, and regulated proteolysis to form a complex regulatory network that integrates chromosome replication, segregation, polar differentiation, and cytokinesis. In this review, we outline the current state of research in the field of C aulobacter development, emphasizing new findings that elaborate how the developmental program is modulated by factors such as the environment or the metabolic state of the cell.