Open AccessHormone‐like factors influencing differentiation of Streptomyces cultures
Author(s) -
Barabas Gy.,
Penyige A.,
Hirano T.
Publication year - 1994
Publication title -
fems microbiology reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.91
H-Index - 212
eISSN - 1574-6976
pISSN - 0168-6445
DOI - 10.1111/j.1574-6976.1994.tb00076.x
Subject(s) - hypha , hormone , biology , streptomyces , antibiotics , mode of action , microbiology and biotechnology , secondary metabolite , spore , biochemistry , bacteria , genetics , gene
Actinomycetes produce and export small autoregulalory molecules, which act like prokaryotic hormones. They can promote or induce sporulation, aerial hyphae formation and antibiotic production. The mode of action of the λ‐lactone AF is partly elucidated, those of the others are not known. These autoregulators (hormones) are effective if exogenously added to culture in proper time of the life cycle and in very low concentration. Since they influence the length of idiophase where secondary metabolites are produced their study may have pratical importance.