Open AccessInduction of the E scherichia coli cysK gene by genetic and environmental factors
Author(s) -
Yamamoto Kaneyoshi,
Oshima Taku,
aka Gen,
Ito Hisao,
Ishihama Akira
Publication year - 2011
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2011.02364.x
Subject(s) - cysteine , escherichia coli , transcription factor , biology , gene , gene expression , genetics , biochemistry , enzyme
Cysteine synthase A encoded by cysK catalyzes the synthesis of cysteine from O ‐acetylserine. Expression of cysK in E scherichia coli is under the control of CysB , a LysR family transcription factor. Herein we showed that the expression of cysK is regulated by several genetic and environmental factors in addition to CysB : two genetic factors, OmpR and CysE , and lithium. Based on the findings, we constructed the high‐level expression system of cysK .