Open AccessGenome sequence of Staphylococcus lugdunensis N920143 allows identification of putative colonization and virulence factors
Author(s) -
Heilbronner Simon,
Holden Matthew T.G.,
van Tonder Andries,
Geoghegan Joan A.,
Foster Timothy J.,
Parkhill Julian,
Bentley Stephen D.
Publication year - 2011
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2011.02339.x
Subject(s) - staphylococcus lugdunensis , virulence , biology , staphylococcus aureus , microbiology and biotechnology , staphylococcus epidermidis , pathogenicity island , genetics , gene , genome , locus (genetics) , whole genome sequencing , staphylococcus , bacteria
Staphylococcus lugdunensis is an opportunistic pathogen related to Staphylococcus aureus and Staphylococcus epidermidis . The genome sequence of S. lugdunensis strain N920143 has been compared with other staphylococci, and genes were identified that could promote survival of S. lugdunensis on human skin and pathogenesis of infections. Staphylococcus lugdunensis lacks virulence factors that characterize S. aureus and harbours a smaller number of genes encoding surface proteins. It is the only staphylococcal species other than S. aureus that possesses a locus encoding iron‐regulated surface determinant (Isd) proteins involved in iron acquisition from haemoglobin.