Open AccessHigh environmental iron concentrations stimulate adhesion and invasive growth of Schizosaccharomyces pombe
Author(s) -
Převorovský Martin,
Staňurová Jana,
Půta František,
Folk Petr
Publication year - 2009
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2009.01515.x
Subject(s) - schizosaccharomyces pombe , adhesion , yeast , schizosaccharomyces , fission , cell adhesion , microbiology and biotechnology , agar , chemistry , agar plate , cell growth , saccharomyces cerevisiae , cell , biology , growth medium , biochemistry , bacteria , genetics , physics , organic chemistry , quantum mechanics , neutron
We have found that a high iron concentration in solid complete cultivation medium potentiates cell–cell and cell–surface adhesion of the fission yeast Schizosaccharomyces pombe . Spotted giant colonies grown on iron‐rich media were found to be more compact and more resistant to washing than those grown on plates with a standard iron content. Furthermore, we have documented that excess environmental iron stimulates the invasive growth of S. pombe (and Saccharomyces cerevisiae ). Three‐dimensional, branched, washing‐resistant structures composed mostly of elongated, but separate fission yeast cells, were formed within the solid agar medium. The degree of both adhesion and invasion displayed a specific, iron concentration‐dependent response. Our results suggest a novel link between iron availability and the intensively studied and important fungal virulence factors, adhesion and invasion.