Open AccessCharacterization of enterocin‐ and salivaricin‐producing lactic acid bacteria from the mammalian gastrointestinal tract
Author(s) -
O'Shea Eileen F.,
Gardiner Gillian E.,
O'Connor Paula M.,
Mills Susan,
Ross R. Paul,
Hill Colin
Publication year - 2009
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2008.01427.x
Subject(s) - bacteriocin , streptococcus salivarius , microbiology and biotechnology , biology , bacteria , lantibiotics , antimicrobial , protease , lactic acid , lactobacillus salivarius , streptococcus suis , streptococcus , biochemistry , enzyme , virulence , gene , genetics
Bacteriocin production may be a factor contributing to bacterial dominance within complex microbial populations and may therefore be a common trait within the gut microbiota. However, of 278 antimicrobial‐producing culturable lactic acid bacteria (LAB) isolated from a range of mammalian intestinal sources in this study, characterization revealed just 23 distinct strains producing bacteriocin‐like inhibitory substances and one Streptococcus hyointestinalis strain producing a potentially novel protease‐insensitive antimicrobial. Three class II bacteriocins previously isolated from intestinal‐derived LAB were identified as enterocin A and two salivaricin P‐like bacteriocins. Moreover, this is the first report of intestinal‐derived Streptococcus salivarius producing variants of the lantibiotic salivaricin A.