Open AccessMycoplasma gallisepticum as the first analyzed bacterium in which RNA is not polyadenylated
Author(s) -
Portnoy Victoria,
Schuster Gadi
Publication year - 2008
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2008.01157.x
Subject(s) - polyadenylation , mycoplasma gallisepticum , biology , rna , mycoplasma , mycoplasma genitalium , bacteria , exosome complex , prokaryote , archaea , genome , genetics , microbiology and biotechnology , non coding rna , gene , virology , chlamydia trachomatis
The addition of poly(A)‐tails to RNA is a phenomenon common to almost all organisms. In addition to most eukaryotic mRNAs possessing a stable poly(A)‐tail, RNA is polyadenylated as part of a degradation mechanism in prokaryotes, organelles, and the eukaryotic nucleus. To date, only very few systems have been described wherein RNA is metabolized without polyadenylation, including several archaea and yeast mitochondria. The minimal genome of the parasitic bacteria, Mycoplasma , does not encode homologs of any known polyadenylating enzyme. Here, we analyze polyadenylation in Mycoplasma gallisepticum . Our results suggest this organism as being the first described bacterium in which RNA is not polyadenylated.