Open AccessAcquisition and diffusion of bla CTX‐M‐9 gene by R478‐IncHI2 derivative plasmids
Author(s) -
García Aurora,
Navarro Ferran,
Miró Elisenda,
Villa Laura,
Mirelis Beatriz,
Coll Pere,
Carattoli Alessandra
Publication year - 2007
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2007.00695.x
Subject(s) - plasmid , salmonella enterica , biology , escherichia coli , gene , microbiology and biotechnology , genetics
Escherichia coli and Salmonella enterica isolates carrying the bla CTX‐M‐9 gene located on plasmids prevailed at the Hospital de la Santa Creu i Sant Pau, Barcelona, Spain in the 1996–1999 period. The bla CTX‐M‐9 ‐carrying plasmids showed a great variability in size, suggesting the mobilization of the gene among different plasmid scaffolds. The aim of the present work was to identify and better characterize the plasmids involved in the spread of the bla CTX‐M‐9 gene. Results showed that the majority of these strains carried plasmids belonging to the IncHI2 incompatibility group. The IncHI2 plasmids were further characterized, and found to be related to the reference IncHI2 plasmid R478.