Open AccessThe structure of the lipid anchor of Campylobacter jejuni polysaccharide
Author(s) -
Corcoran Adrian T.,
Annuk Heidi,
Moran Anthony P.
Publication year - 2006
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2006.00177.x
Subject(s) - campylobacter jejuni , microbiology and biotechnology , polysaccharide , chemistry , campylobacter , lipid a , extracellular polysaccharide , extracellular , bacteria , biology , biochemistry , genetics
Campylobacter jejuni is a leading cause of gastroenteritis in humans. Campylobacter jejuni produces extracellular polysaccharides that have been characterized structurally and shown to be independent of lipopolysaccharides. Furthermore, it has been suggested that these C. jejuni polysaccharides are capsular in nature, although their lipid anchor has not been identified. In this report, the occurrence of a lipid‐linked capsular‐like polysaccharide in C. jejuni is conclusively shown, and the lipid anchor identified as dipalmitoyl‐glycerophosphate.