Open AccessA comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis
Author(s) -
Spears Kevin J.,
Roe Andrew J.,
Gally David L.
Publication year - 2006
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2006.00119.x
Subject(s) - enteropathogenic escherichia coli , virulence , bacterial adhesin , microbiology and biotechnology , biology , escherichia coli , effector , carriage , virology , gene , genetics , immunology , medicine , pathology
This review covers enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) infections, focusing on differences in their virulence factors and regulation. While Shiga‐toxin expression from integrated bacteriophages sets EHEC apart from EPEC, EHEC infections often originate from asymptomatic carriage in ruminants whereas human EPEC are considered to be overt pathogens and more host‐restricted. In part, these differences reflect variation in adhesin repertoire, type III‐secreted effectors and the way in which these factors are regulated.