Open AccessArginine inhibits Na + ‐driven flagellar motors of alkaliphilic Bacillus
Author(s) -
Atsumi Tatsuo,
Yoshimura Fuminobu,
Sugiyama Shigeru
Publication year - 2006
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2006.00117.x
Subject(s) - arginine , chemistry , bacillus (shape) , biochemistry , microbiology and biotechnology , biology , amino acid
l ‐arginine has attracted a great deal of attention as an agent for refolding denatured proteins, and the mildness of its effects offer hope for a wide range of potential applications for this substance, including medicines with few side effects. We report that both l ‐ and d ‐arginine inhibits Na + ‐driven flagellar motors of alkaliphilic Bacillus by competing with Na + , which we take as evidence that arginine specifically binds to a molecular target.