Open AccessMolecular characterization of extraintestinal pathogenic Escherichia coli (ExPEC) pathogenicity islands in F165‐positive E. coli strain from a diseased animal
Author(s) -
Dezfulian Hojabr,
Tremblay Donald,
Harel Josée
Publication year - 2004
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2004.tb09773.x
Subject(s) - operon , escherichia coli , biology , gene , pathogenicity island , genetics , l arabinose operon , bacterial adhesin , gal operon , fimbria , gene cluster , chromosome , microbiology and biotechnology
Septicemic Escherichia coli 4787 (O115: K‐: H51: F165) of porcine origin possess gene clusters related to extraintestinal E. coli fimbrial adhesins. This strain produces two fimbriae: F165 1 and F165 2 . F165 1 (Prs‐like) belongs to the P fimbrial family, encoded by foo operon and F165 2 is a F1C‐like encoded by fot operon. Data from this study suggest that these two operons are part of two PAIs. PAI I 4787 includes a region of 20 kb, which not only harbors the foo operon but also contains a potential P4 integrase gene and is located within the pheU tRNA gene, at 94 min of the E. coli chromosome. PAI II 4787 includes a region of over 35 kb, which harbors the fot operon, iroBCDEN gene clusters, as well as part of microcin M genes and nonfunctional mobility genes. PAI II 4787 is found between the proA and yagU at 6 min of the E. coli chromosome.