Open AccessScreening for biologically active metabolites with endosymbiotic bacilli isolated from arthropods
Author(s) -
Gebhardt Klaus,
Schimana Judith,
Müller Johannes,
Fiedler HansPeter,
Kallenborn Helmut G,
Holzenkämpfer Meike,
Krastel Philipp,
Zeeck Axel,
Vater Joachim,
Höltzel Alexandra,
Schmid Dietmar G,
Rheinheimer Joachim,
Dettner Konrad
Publication year - 2002
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2002.tb11475.x
Subject(s) - biology , bacteria , bacilli , microbiology and biotechnology , metabolism , biological activity , fungus , bacillus (shape) , microbial metabolism , secondary metabolism , biochemistry , biosynthesis , botany , enzyme , in vitro , genetics
Abstract Endosymbiotic bacteria from the genus Bacillus were isolated from different compartments of the gut of various members of insects (Hexapoda) and millipedes (Diplopoda). They were grown in submerged culture and investigated by biological assays and HPLC‐diode array analysis regarding their production of bioactive metabolites, which were isolated and determined in structure. Known compounds and yet unknown derivatives from the primary metabolism were detected, as well as antibacterially and antifungally acting peptide antibiotics.