
The autolysin of Porphyromonas gingivalis is involved in outer membrane vesicle release
Author(s) -
Hayashi Junichiro,
Hamada Nobushiro,
Kuramitsu Howard K
Publication year - 2002
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2002.tb11438.x
Subject(s) - autolysin , porphyromonas gingivalis , vesicle , bacterial outer membrane , microbiology and biotechnology , mutant , chemistry , membrane , biology , bacteria , biochemistry , escherichia coli , gene , genetics
An autolysin mutant of Porphyromonas gingivalis was constructed and its outer membrane vesicle production was compared to that of wild‐type strain 381. The autolysin mutant produced elevated levels of vesicles relative to the parental strain. It is suggested that vesicle formation of this organism may be regulated by cell wall turnover.