Open AccessThe level of Yop proteins secreted by Yersinia enterocolitica is changed in maltose mutants
Author(s) -
Brzostek Katarzyna,
Raczkowska Adrianna
Publication year - 2001
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2001.tb10869.x
Subject(s) - maltose , yersinia enterocolitica , mutant , secretion , maltose binding protein , microbiology and biotechnology , plasmid , biology , secretory protein , gene , biochemistry , bacteria , recombinant dna , enzyme , genetics , fusion protein
Enteropathogenic Yersinia enterocolitica strains express a set of plasmid‐encoded proteins called Yops, involved in pathogenicity. We studied the influence of the maltose system on the production of Yop proteins and found that the level of Yop proteins of Y. enterocolitica O:9 was reduced in the presence of maltose. Transposon insertion mutants impaired with the maltose transport activity showed a decreased level in the production of Yop proteins. The transcription of the yopH gene for YopH phosphatase in these maltose mutants was unchanged and revealed a maltose mutation impaired in the secretion of Yop proteins instead of their expression.