Open AccessAdherence of ovine and human Bordetella parapertussis to continuous cell lines and ovine tracheal organ culture
Author(s) -
Lund Sarah J.,
Rowe Helen A.,
Parton Roger,
Donachie Willie
Publication year - 2001
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2001.tb09469.x
Subject(s) - organ culture , biology , cell culture , microbiology and biotechnology , genetics , in vitro
The adherence of ovine and human isolates of Bordetella parapertussis to ovine and human continuous culture cell lines and to ovine tracheal organ culture was compared. Adherence to non‐ciliated respiratory continuous culture cells did not reveal any host‐specificity of the isolates. In contrast, adherence of ovine B. parapertussis strains to ciliated ovine tracheal organ culture was significantly greater than that of human strains. These results indicate that tracheal organ culture is a useful tool for studying host‐specific adherence of B. parapertussis and suggest that adherence of B. parapertussis to ciliated epithelia is species‐specific making it unlikely that the transfer of B. parapertussis between humans and sheep will result in an infection.