Open AccessInducible stx2 phages are lysogenized in the enteroaggregative and other phenotypic Escherichia coli O86:HNM isolated from patients
Author(s) -
Iyoda Sunao,
Tamura Kazumichi,
Itoh Kenichiro,
Izumiya Hidemasa,
Ueno Nobuhiro,
Nagata Kohji,
Togo Masami,
Terajima Jun,
Watanabe Haruo
Publication year - 2000
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2000.tb09311.x
Subject(s) - stx2 , microbiology and biotechnology , escherichia coli , biology , shiga toxin , enteroaggregative escherichia coli , fimbria , diarrhea , bloody diarrhea , strain (injury) , genotype , enteropathogenic escherichia coli , enterobacteriaceae , virology , gene , genetics , medicine , anatomy
We characterized two Shiga toxin‐producing Escherichia coli (STEC) O86:HNM isolates from a patient with hemolytic uremic syndrome (HUS) or bloody diarrhea. Both of them did not possess the eaeA gene. However, the isolate from a HUS patient carried genetic markers of enteroaggregative E. coli (EAEC) and showed aggregative adherence pattern to HEp‐2 cells. The other isolate from bloody diarrhea, which was negative with EAEC markers, was diffusely adhered to HEp‐2 cells. The stx2 gene in both E. coli O86:HNM strains was encoded in each infectious phage, which was partially homologous to that of strain EDL933, a STEC O157:H7. These results will help to explain the genotypic divergences of STEC.