Open AccessHopanoids are formed during transition from substrate to aerial hyphae in Streptomyces coelicolor A3(2)
Author(s) -
Poralla Karl,
Muth Günther,
Härtner Thomas
Publication year - 2000
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.2000.tb09212.x
Subject(s) - streptomyces coelicolor , mycelium , hypha , hopanoids , spore , microbiology and biotechnology , biology , bacterial outer membrane , sporogenesis , streptomyces , mutant , strain (injury) , membrane , actinomycetales , chemistry , botany , biochemistry , bacteria , gene , escherichia coli , paleontology , genetics , structural basin , anatomy , source rock
Streptomyces coelicolor A3(2) contains a cluster of putative isoprenoid and hopanoid biosynthetic genes. The strain does not produce the pentacyclic hopanoids in liquid culture but produces them on solid medium when sporulating. Mutants defective in the formation of aerial mycelium and spores ( bld ), with the exception of bldB , do not synthesize hopanoids, whereas mutants, which form aerial mycelium but no spores ( whi ), do. The membrane condensing hopanoids possibly may alleviate stress in aerial mycelium by diminishing water permeability across the membrane.