Open AccessFramePlot: a new implementation of the Frame analysis for predicting protein‐coding regions in bacterial DNA with a high G+C content
Author(s) -
Ishikawa Jun,
Hotta Kunimoto
Publication year - 1999
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1999.tb13576.x
Subject(s) - coding region , coding (social sciences) , computational biology , dna , sequence database , protein sequencing , sequence analysis , biology , gc content , genetics , computer science , peptide sequence , mathematics , gene , genome , statistics
FramePlot is a web-based tool for predicting protein-coding regions in bacterial DNA with a high G + C content, such as Streptomyces. The graphical output provides for easy distinction of protein-coding regions from non-coding regions. The plot is a clickable map. Clicking on an ORF provides not only the nucleotide sequence but also its deduced amino acid sequence. These sequences can then be compared to the NCBI sequence database over the Internet. The program is freely available for academic purposes at http://www.nih.go.jp/jun/cgi-bin/frameplot.pl.