Open AccessStaphylococcus aureus adhesion to bone matrix and bone‐associated biomaterials
Author(s) -
Hudson Michael C,
Ramp Warren K,
Frankenburg Kelly P
Publication year - 1999
Publication title -
fems microbiology letters
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 151
eISSN - 1574-6968
pISSN - 0378-1097
DOI - 10.1111/j.1574-6968.1999.tb13514.x
Subject(s) - staphylococcus aureus , bacterial adhesin , bone matrix , microbiology and biotechnology , adhesion , matrix (chemical analysis) , chemistry , bacteria , biology , cartilage , escherichia coli , biochemistry , anatomy , genetics , organic chemistry , chromatography , gene
Staphylococcus aureus is a frequent cause of orthopedic infections in humans. The bacterium expresses several adhesins that facilitate bacterial binding to the bone matrix and to bone implant biomaterials coated with host plasma constituents. The relevant S. aureus adhesins are termed microbial surface components recognizing adhesive matrix molecules (MSCRAMMs) and specific MSCRAMMs are involved in bone and joint infections.